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- Drugs for organ transplant patients recalled because some capsules may be empty
The company warns of potentially fatal consequences By Mark Huffman of ConsumerAffairs December 30, 2024 Astellas Pharma US, Inc. has issued a recall for one lot of PROGRAF 0.5mg (tacrolimus) and one lot of ASTAGRAF XL 0.5mg (tacrolimus extended-release) capsules. These products are being recalled because the bottles may contain empty capsules. Transplant patients who consume empty PROGRAF or ASTAGRAF XL capsules may experience rejection of the transplanted organ, tissue, or cells, due to underimmunosuppression. In the case of life-sustaining organ transplants such as a heart transplant, for which there is no permanent substitute such as hemodialysis in the case of a failed kidney transplant, if the transplant fails, the consequences of rejection initiated by ingesting empty capsules may be fatal. Astellas has not received any reports of adverse events related to this recall. PROGRAF and ASTAGRAF XL are immunosuppressive medicines, used in conjunction with other medicines, to help… ...[TheTopNews] Read More.2 days ago - Avanti West Coast strike to hit New Year’s Eve trains
Rail passengers will face a "significantly reduced" service due to a strike by train managers. ...[TheTopNews] Read More.2 days ago - Monster of 2024: The Relentless Pressure to Download More Apps
My cellphone’s apps serve as my alarm clock, meteorologist, GPS, and e-reader. FaceTime is the portal to my nieces who live 500 miles away. Chase Mobile is the reason I seldom deposit checks at a physical bank. Hinge has provided me with an overabundance of dating horror stories and—after copious swiping—an incredible partner. Let me declare at the onset, these apps are useful—even pretty good! This screed is not about them. My grievance focuses on every company in the world believing its products either should or must be accessed through a standalone app. Want to buy a single Major League Baseball ticket on your smartphone? Add that app to your already chaotic home screen! Need to charge your electric-powered rental car? Hah! Don’t think that only one app will do. Each of the various charging companies uses a different app. My app annoyance blossomed into sheer disdain after a… ...[TheTopNews] Read More.2 days ago - Chemtrail Conspiracy Theories: Here’s Why RFK Jr. Is Watching the SkiesThis story was originally published by the Guardian and is reproduced here as part of the Climate Desk collaboration. A conspiracy theory that airplanes are leaving nefarious “chemtrails” in their wake due to a sinister government plot has been given fresh impetus in the US amid a swirl of concerns and confusion about proposals to geoengineer a response to the climate crisis. State legislation to ban what some lawmakers call chemtrails has been pushed forward in Tennessee and, most recently, Florida. Meanwhile, Robert F. Kennedy Jr., who has expressed interest in the conspiracy theory on social media and his podcast, is set to be at the heart of Donald Trump’s new administration following his nomination as health secretary. “We are going to stop this crime,” Kennedy, who is known for his contrarian stances on vaccines and offshore wind farms, wrote about chemtrails on X in August. The former Democrat turned Trump ally said on his podcast last year that it was “kind… ...[TheTopNews] Read More.2 days ago
- The Climate Crisis Exposed People to Six More Weeks of Dangerous Heat in 2024This story was originally published by the Guardian and is reproduced here as part of the Climate Desk collaboration. The climate crisis caused an additional six weeks of dangerously hot days in 2024 for the average person, supercharging the fatal impact of heat waves around the world. The effects of human-caused global heating were far worse for some people, an analysis by World Weather Attribution (WWA) and Climate Central has shown. Those in the Caribbean and Pacific island states were the hardest hit. Many endured about 150 more days of dangerous heat than they would have done without global heating, almost half the year. Nearly half the world’s countries endured at least two months of high-risk temperatures. Even in the least affected places, such as the UK, US, and Australia, the carbon pollution from fossil fuel burning has led to an extra three weeks of elevated temperatures. Worsened heatwaves are the deadliest consequence of the climate… ...[TheTopNews] Read More.2 days ago
- Hero of 2024: Randy Betz Jr., @flyfishdelawhereThe staff of Mother Jones is, once again, rounding up the heroes and monsters of the past year. Importantly, this is a completely non-exhaustive and subjective list, giving our reporters a chance to write about something that brought joy or discontent. Enjoy. There’s a lot that can scare off the newbie fly fisher. First, the gear: the rod and reel, of course, but also the fly line, the leader, the tippet, the waders, the boots, and—above all—the flies, the infinite permutations of size and color and material and hook. Then there’s the cast: a seemingly endless pursuit of the right rhythm, the correct accelerate-to-a-stop, pause, accelerate-to-a-stop that stretches the line out in front of you and lands the fly gently on the water. There’s also learning to read your local streams: Even drifting the right fly at the correct depth won’t matter if nobody’s home. And finally, entomology: You can catch trout without… ...[TheTopNews] Read More.2 days ago
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