In 2024, San Francisco's Christian McCaffrey suffered from tendinitis in his Achilles and missed eight games due to that injury. He missed even more time battling a right knee issue and ultimately, sat out most of the year. But in 2025, he came back with a vengeance. Last season, CMC amassed a total of 2,126 yards — including 1,202 rushing yards and 10 rushing touchdowns. As a result, the dual-threat running back earned the NFL Comeback Player of the Year award. Now, bettors are asking which player will take home the award at the end of the 2026 season. Here are the odds at DraftKings Sportsbook as of Sept. 28. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. Patrick Mahomes: -270 (bet $10 to win $13.70 total)Kyler Murray: +1500 (bet $10 to win $160 total)Aaron Donald: +1800 (bet $10 to win $190 total)Michael Penix Jr.: +1800 (bet $10 to win $190 total)George Kittle: +2000 (bet $10 to win $210 total)Fred Warner: +2500 (bet $10 to win $260 total)Deshaun Watson: +2500 (bet $10 to win $260 total)Brock Bowers: +2500 (bet $10 to win $260 total)Daniel Jones: +2800 (bet $10 to win $290 total)Cam Skattebo: +2800 (bet $10 to win $290 total)Micah Parsons: +3000 (bet $10 to win $310 total)Malik Nabers: +3000 (bet $10 to win $310 total) Here's what to know about this oddsboard: The Favorite: Last season, Patrick Mahomes tore his ACL and LCL in the Chiefs' Week 15 game against the Chargers. He underwent surgery the next day, but fast-forward to this season, and he's already proving his value to the Chiefs. Through three weeks, he's racked up 812 passing yards and seven touchdowns (both tied for fifth). And although it's early in the year, K.C. currently boasts perfect record at 3-0. Aaron's Back: Although he missed the Rams' Week 1 game in Australia — a 27-7 loss to the 49ers — Aaron Donald has come out of retirement to join his former team. Donald is a three-time Defensive Player of the Year winner, and his presence will be sorely needed after it was announced that two-time DPOY winner Myles Garrett will miss several weeks with a knee injury. [TheTopNews] Read More.
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