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- Early Parkinson’s warning signs may be hiding in the gut, study finds
Specific bacteria in the gut could predict a person’s risk of developing Parkinson’s disease years before symptoms appear, new research suggests.Led by researchers from University College London (UCL), an observational study analyzed the gut microbes of 271 patients in the U.K. who had been diagnosed with Parkinson’s.Also included in the study were 43 carriers of the GBA1 variant, which has been linked to an almost 30 times higher risk of Parkinson’s disease. These participants did not have symptoms of the disease. There was also a control group of 150 healthy participants without the gene.STUDY FINDS EVIDENCE OF MICROPLASTICS IN BRAINS AND OTHER ORGANSBased on fecal samples, more than one-quarter of gut microbes — bacteria and other microorganisms in the digestive tract — were in different amounts for people with Parkinson’s disease compared to healthy individuals, according to a press release.Non-symptomatic people carrying the Parkinson’s gene also had microbial changes that resembled an "intermediate" stage of the disease, which suggests that microbial changes may happen prior to symptoms emerging.Those who reported eating a more diverse and balanced diet were less likely to have microbiome patterns associated with higher Parkinson’s risk, the researchers found.The findings, which were published in Nature Medicine, were also seen in over 1,400 participants across the U.K., Korea and Turkey, suggesting that the microbial changes are consistent across different cultures and dietary patterns."Parkinson’s disease is a major cause of disability worldwide, and the fastest growing neurodegenerative disease in terms of prevalence and mortality," lead author Professor Anthony Schapira of the UCL Queen Square Institute of Neurology said in the release. "There is an urgent need to develop treatments that can stop or slow the disease’s progression."ALZHEIMER'S RISK COULD RISE WITH COMMON CONDITION AFFECTING MILLIONS, STUDY FINDSPatients with Parkinson's are known to have "significant gut abnormalities," according to Dr. Earnest Lee Murray, a board-certified neurologist at Jackson-Madison County General Hospital in Jackson, Tennessee.One of those is severe constipation, which can occur several years before tremors and other symptoms. "There has long been a theory about the gut-brain axis and whether or not the pathology for Parkinson's starts in the gut decades before stereotypical features are noted," Murray, who was not involved in the research, told Fox News Digital.The neurologist said the study sets the stage for additional research exploring the gut-brain axis theory, which could determine whether early pre-symptomatic treatments could prevent or mitigate the risk of developing Parkinson's later in… [TheTopNews] Read More.2 days ago - Avoiding Winter Pileups: How Truck Drivers Can Stay Safe on Icy Roads
Understanding Chain-Reaction Crashes and How to Avoid Them Winter pileups are often misunderstood as a single accident, but they are actually a series of chain-reaction crashes. According to safety experts, these incidents typically involve 20 to 25 smaller collisions happening in rapid succession. As a result, what starts as one minor mistake can quickly escalate into a major highway shutdown. These crashes are usually triggered when drivers travel too fast and too close together during poor weather conditions. Therefore, when one driver brakes suddenly, others do not have enough time or distance to react. In winter driving, where traction is limited, this often leads to a dangerous cascade of collisions. Why Winter Pileups Are Becoming More Severe Although winter crashes are not new, their scale appears to be increasing. Experts point to several key factors contributing to this trend: More vehicles on the road than ever before Increased pressure to maintain schedules Riskier driving behaviors such as tailgating and drafting Overconfidence in handling winter conditions In addition, reduced visibility plays a major role. When drivers cannot see more than a short distance ahead, they lose reference points and struggle to react in time. Consequently, even experienced drivers can find themselves caught in dangerous situations. Key Warning Signs Drivers Should Watch For Recognizing early warning signs is critical for avoiding pileups. In many cases, conditions can change rapidly, leaving little time to react. Drivers should be alert to: Sudden drops in visibility due to snow or blowing wind Disappearing taillights ahead Vehicles slowing down or bunching together Loss of traction or vehicle control Therefore, once visibility drops to 15 to 50 feet, the risk level increases significantly. At this point, continuing to drive may become unsafe. Defensive Driving Strategies for Winter Conditions Defensive driving becomes essential during winter weather. While avoiding the road entirely is the safest option, it is not always practical. As a result, drivers must adjust their behavior to reduce risk. Recommended safety actions include: Turn on hazard lights when visibility drops Ease off the throttle instead of braking suddenly Maintain a greater following distance Avoid “pack driving” with other vehicles Move to the right lane and prepare to exit In addition, if strong winds begin pushing the trailer, it is a clear signal to stop driving. Continuing in such conditions can lead to loss of control and potential jackknife accidents.… [TheTopNews] Read More.2 days ago - Spring Housing Market Holds Its Ground Despite Economic Headwinds, According to ...
Prices Fall for a Sixth Straight Month, and Fewer Price Cuts Signal Sellers are Coming to Market More Realistic Pricing [TheTopNews] Read More.2 days ago - How Good Is Google’s Gemini AI at Making Travel Plans?
Gemini is a digital Swiss Army knife for planning flights, activities and routes, but it isn’t perfect. Why did it forget to put underwear on the packing list? [TheTopNews] Read More.2 days ago - Iceland’s Pools and Hot Tubs Are Now UNESCO-Recognized. Some Locals Aren’t T...Iceland’s swimming pools and hot tubs serve as hubs of social life, a cultural distinction recently honored by UNESCO. Some Icelanders aren’t so thrilled. [TheTopNews] Read More.2 days ago
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Specific bacteria in the gut could predict a person’s risk of developing Parkinson’s disease years before symptoms appear, new research suggests.Led by researchers from University College London (UCL), an observational study analyzed the gut microbes of 271 patients in the U.K. who had been diagnosed with Parkinson’s.Also included in the study were 43 carriers of the GBA1 variant, which has been linked to an almost 30 times higher risk of Parkinson’s disease. These participants did not have symptoms of the disease. There was also a control group of 150 healthy participants without the gene.STUDY FINDS EVIDENCE OF MICROPLASTICS IN BRAINS AND OTHER ORGANSBased on fecal samples, more than one-quarter of gut microbes — bacteria and other microorganisms in the digestive tract — were in different amounts for people with Parkinson’s disease compared to healthy individuals, according to a press release.Non-symptomatic people carrying the Parkinson’s gene also had microbial changes that resembled an "intermediate" stage of the disease, which suggests that microbial changes may happen prior to symptoms emerging.Those who reported eating a more diverse and balanced diet were less likely to have microbiome patterns associated with higher Parkinson’s risk, the researchers found.The findings, which were published in Nature Medicine, were also seen in over 1,400 participants across the U.K., Korea and Turkey, suggesting that the microbial changes are consistent across different cultures and dietary patterns."Parkinson’s disease is a major cause of disability worldwide, and the fastest growing neurodegenerative disease in terms of prevalence and mortality," lead author Professor Anthony Schapira of the UCL Queen Square Institute of Neurology said in the release. "There is an urgent need to develop treatments that can stop or slow the disease’s progression."ALZHEIMER'S RISK COULD RISE WITH COMMON CONDITION AFFECTING MILLIONS, STUDY FINDSPatients with Parkinson's are known to have "significant gut abnormalities," according to Dr. Earnest Lee Murray, a board-certified neurologist at Jackson-Madison County General Hospital in Jackson, Tennessee.One of those is severe constipation, which can occur several years before tremors and other symptoms. "There has long been a theory about the gut-brain axis and whether or not the pathology for Parkinson's starts in the gut decades before stereotypical features are noted," Murray, who was not involved in the research, told Fox News Digital.The neurologist said the study sets the stage for additional research exploring the gut-brain axis theory, which could determine whether early pre-symptomatic treatments could prevent or mitigate the risk of developing Parkinson's later in… [TheTopNews] Read More.
2 days ago
Understanding Chain-Reaction Crashes and How to Avoid Them Winter pileups are often misunderstood as a single accident, but they are actually a series of chain-reaction crashes. According to safety experts, these incidents typically involve 20 to 25 smaller collisions happening in rapid succession. As a result, what starts as one minor mistake can quickly escalate into a major highway shutdown. These crashes are usually triggered when drivers travel too fast and too close together during poor weather conditions. Therefore, when one driver brakes suddenly, others do not have enough time or distance to react. In winter driving, where traction is limited, this often leads to a dangerous cascade of collisions. Why Winter Pileups Are Becoming More Severe Although winter crashes are not new, their scale appears to be increasing. Experts point to several key factors contributing to this trend: More vehicles on the road than ever before Increased pressure to maintain schedules Riskier driving behaviors such as tailgating and drafting Overconfidence in handling winter conditions In addition, reduced visibility plays a major role. When drivers cannot see more than a short distance ahead, they lose reference points and struggle to react in time. Consequently, even experienced drivers can find themselves caught in dangerous situations. Key Warning Signs Drivers Should Watch For Recognizing early warning signs is critical for avoiding pileups. In many cases, conditions can change rapidly, leaving little time to react. Drivers should be alert to: Sudden drops in visibility due to snow or blowing wind Disappearing taillights ahead Vehicles slowing down or bunching together Loss of traction or vehicle control Therefore, once visibility drops to 15 to 50 feet, the risk level increases significantly. At this point, continuing to drive may become unsafe. Defensive Driving Strategies for Winter Conditions Defensive driving becomes essential during winter weather. While avoiding the road entirely is the safest option, it is not always practical. As a result, drivers must adjust their behavior to reduce risk. Recommended safety actions include: Turn on hazard lights when visibility drops Ease off the throttle instead of braking suddenly Maintain a greater following distance Avoid “pack driving” with other vehicles Move to the right lane and prepare to exit In addition, if strong winds begin pushing the trailer, it is a clear signal to stop driving. Continuing in such conditions can lead to loss of control and potential jackknife accidents.… [TheTopNews] Read More.
2 days ago
Prices Fall for a Sixth Straight Month, and Fewer Price Cuts Signal Sellers are Coming to Market More Realistic Pricing [TheTopNews] Read More.
2 days ago
Gemini is a digital Swiss Army knife for planning flights, activities and routes, but it isn’t perfect. Why did it forget to put underwear on the packing list? [TheTopNews] Read More.
2 days ago
Iceland’s swimming pools and hot tubs serve as hubs of social life, a cultural distinction recently honored by UNESCO. Some Icelanders aren’t so thrilled. [TheTopNews] Read More.
2 days ago
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