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- Popular weight-loss drugs linked to unexpected male fertility benefit
Taking a GLP-1 medication for weight loss may improve male fertility, according to experts.Research presented this week at ENDO 2026, the Endocrine Society’s annual meeting in Chicago, explored how obesity is strongly linked to fertility problems in men.Excess weight can contribute to dysregulation of the hypothalamic-pituitary-gonadal (HPG) axis — the hormone system that regulates testosterone production — and functional hypogonadism, a condition in which testosterone levels are abnormally low because of disrupted hormone signaling. These changes can also impair semen quality.WEIGHT-LOSS MEDICATIONS COULD IMPACT SEXUAL HEALTH IN UNEXPECTED WAYSThe researchers evaluated how GLP-1 weight-loss drugs impact reproductive hormones and metabolic outcomes, analyzing data of men between the ages of 18 and 65 who were taking one of the medications, according to a press release.The systematic review of five randomized controlled trials focused on measuring testosterone, brain hormones involved in testosterone and sperm production, and a protein that carries sex hormones in the blood. Semen quality, weight and BMI, cholesterol and blood sugar were also measured.The results suggested that GLP-1 medications do not suppress male hormones. Men with obesity and low testosterone linked to obesity may experience improved testosterone, sperm quality and metabolic health, especially during weight loss.In one four-week study, dulaglutide showed no significant changes in reproductive hormones or sexual function.In a separate 16-week trial, liraglutide improved hormones in obese men with functional hypogonadism, meaning low testosterone was likely related to obesity. The review found that liraglutide was better for health outcomes than hormone replacement therapy.CLICK HERE FOR MORE HEALTH STORIESAnother liraglutide study reported improved sperm concentration and count.A 24-week trial of semaglutide, known commercially as Ozempic and Wegovy, saw improvement in sperm shape and bad cholesterol, while preserving total testosterone.As only five trials were included, the small evidence base suggests more research is necessary to prove further association.CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTERIn an abstract of the research, the authors summed up that GLP-1s "do not appear to acutely suppress the male HPG axis and may improve reproductive hormones and semen parameters in obese hypogonadal men, largely within the context of weight loss.""However, evidence remains limited and heterogeneous, underscoring the need for larger RCTs explicitly powered to assess male reproductive outcomes," they wrote.Dr. Anthony Puopolo, men’s health expert and lead medical provider for RexMD, reflected on these findings in an interview with Fox News Digital."This provides early evidence that GLP-1 medications taken by obese men with… [TheTopNews] Read More.3 days ago - Stamford Marketing Firm Launches Four-Part System to Help Local Businesses Rank ...
[TheTopNews] Read More.3 days ago - SNAP restrictions could change what shoppers buy — and food giants are watchin...
SNAP food restrictions are spreading to more states, pressuring major food and beverage as consumers shift spending away from soda, candy and processed foods. [TheTopNews] Read More.3 days ago - The Eternal Allure of the Rabbit Hole
Sylvia Meagher was 44 years old in the fall of 1965 and lived alone, except for her cat, Allegra, named after the ballet dancer Allegra Kent. She commuted from her one-bedroom apartment in the West Village to the United Nations, where she’d been working for nearly two decades at the World Health Organization. Although Meagher was a bureaucrat, her sensibilities were bohemian. She was acquainted with many of the painters, musicians, and writers who lived near her. In her foyer, Meagher displayed a painting of a nude figure given to her by a neighbor, the expressionist Alexander Dobkin. But the focal point of her living space was a bookcase laden with 26 reference volumes bound in dark-blue cloth. These were the supplemental materials of the Warren Commission Report. Only a few hundred private citizens in the United States purchased a copy of the 18,000-page, 54-pound series as soon as the Government Printing Office made it available. Far fewer had read it end to end. Perhaps only Meagher had nearly memorized it. Released in September 1964, the Warren Report was the government’s official story of the assassination of President John F. Kennedy. The report’s key finding was that an odd, angry, 24-year-old assassin, Lee Harvey Oswald, had acted alone, for reasons nobody could quite figure out. The public evidence—exhibits, hearings, et cetera—was piled into the supplementary volumes. The government did not furnish an index, making casual inquiry incredibly difficult.During the year since she’d received delivery of her crate of the volumes, Meagher had been reading and rereading. She’d remade her living room into an office, with filing cabinets for notes and correspondence, and a large desk positioned near the fireplace. She took a volume on the subway each day and made notes on a clipboard; she worked during her commute, during her lunch hour, at night when she got home, and every weekend. One of her friends, the French journalist Leo Sauvage, called her “the only person in the world who really knows every item hidden in the 26 volumes of Hearings and Exhibits.” Meagher was neither a conspiracy theorist nor a wannabe detective. She considered herself a “critic” of the Warren Report. A New Deal liberal with a far-left social circle, she had been subjected to questioning by a loyalty board during the Red Scare, putting her at odds with her government. When the president’s assassin was identified as a… [TheTopNews] Read More.3 days ago - Our Hidden Fungal Networks Could Reach Beyond the Solar System
This story was originally published by Inside Climate News and is reproduced here as part of the Climate Desk collaboration. Hidden underground around the world lie 110 quadrillion kilometers of arbuscular mycorrhizal fungal networks—webs of ultrathin threads that, if connected in a single line, would stretch almost a billion times the distance between the Earth and the sun, according to new research published in Science on June 11. These fungal communities form intimate relationships with the roots of plants, which they provide with nutrients like phosphorus and nitrogen in exchange for carbon, 1 billion tons of which the networks sequester underground annually, previous research has found. If the fungal network wasn’t storing it, that carbon would be warming the atmosphere. But those networks have never been mapped globally until now. The new study led by Society for the Protection of Underground Networks (SPUN), an organization founded to map mycorrhizal fungi networks, used a combination of literature review, soil samples from around the globe, machine learning, and laboratory testing to estimate the distribution and mass of these systems and map where they are densest. “This is the moment where we went from knowing that this system exists to really knowing where it is, how dense it is and where it’s been,” said Toby Kiers, executive director and co-founder of SPUN and a co-author of the study. “You’re getting a win-win. The plants are growing better, and carbon’s being drawn down. ” For decades, researchers have known arbuscular mycorrhizal fungi form intimate symbiotic relationships with roughly 80 percent of the globe’s plant species and are found nearly everywhere plants are. But the extent of those networks and where they are densest, such as grasslands, and where they are being lost, like in agricultural areas, hasn’t been well understood until now. “[The study] helps us come to grips with how important these below ground organisms can be to everything that we see above ground,” said James Bever, a professor of ecology and evolutionary biology at the University of Kansas who studies the interactions between plants and microbes like fungi in soils but was not involved in the new study. Justin Stewart, an evolutionary ecologist at SPUN and lead author of the study, said previous studies the team had done on biodiversity of fungi were similar to asking someone to describe the forest outside their home. “They could say, ‘Well, there are three tree species in it.’ That’s great. That tells me about… [TheTopNews] Read More.3 days ago - The Seven-Headed Hydra at the End of FinanceSpaceX had its initial public offering last week. Now Elon Musk is a trillionaire on paper. But what is SpaceX? On one level, of course, SpaceX is a company that builds rockets and spacecraft and launches them into space. (Occasionally the rockets explode.) It is also the company that birthed Starlink, a satellite-internet business that generated more than $11 billion in revenue last year.But the company can be defined in many ways. SpaceX is a financial instrument for Musk. Before the IPO, SpaceX acquired xAI, Musk’s artificial-intelligence company, which itself acquired X, the social-media site, back in 2025. The maneuver allowed SpaceX to claim that it believed it had “the largest actionable total addressable market in human history”: $28.5 trillion, to be precise. $26.5 trillion of that, according to the filing, would come from AI infrastructure and applications, meaning not from SpaceX’s core business of aerospace engineering and satellites.Maybe most important, SpaceX is a story, even a meme. Musk is arguably a better salesman than an inventor, and what he began selling early on was a techno-utopian dream—of himself as a Tony Stark–style genius, of an environment-saving EV revolution, of securing a future for humanity by getting us all to Mars. He intuitively understands the warped dynamics of the attention economy. Ben Tarnoff and Quinn Slobodian, the authors of the book Muskism, describe his strategy on social media as “trolling is infrastructure”: “Every joke, every poll is a stress test of responsiveness,” they argue. “Can he still move markets with a post?” Dogecoin, the cryptocurrency based on a 13-year-old meme of a shiba inu, is the shining example of Musk’s ability to lavish attention on something—in this case, a fake asset whose entire joke was that it was worthless—and make it worth more to others as a result.SpaceX is obviously not Dogecoin. Its rocket business is a genuine success story, as is Starlink. But the company’s appeal, particularly in the face of setbacks, is also reliant on a combination of story and Musk’s own image in ways that are not necessarily connected to reality. Musk has frequently set unrealistic timelines for projects, including putting a spacecraft on Mars by 2018. Last year, SpaceX’s flagship rocket underwent a “rapid unscheduled disassembly” on three test flights (it blew up). But SpaceX’s IPO filing was more oriented around its future ambitions and assumed triumphs, such as its desire to mine asteroids, promote space… [TheTopNews] Read More.3 days ago
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